Pain that persists for more than three months beyond expected healing time, involving changes in the nervous system that can amplify pain signals and reduce pain tolerance.
Chronic pain involves neuroplastic changes in the spinal cord and brain that alter pain processing, a phenomenon known as central sensitization. Effective management requires a multimodal approach addressing the biological, psychological, and social factors that perpetuate pain. This may include physical therapy, regenerative medicine, nutritional support, and mind-body techniques.
Patients with pain lasting longer than three months that has not resolved with standard treatments and is affecting daily function and quality of life.
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